Haoyu Cheng, Ph.D., assistant professor of biomedical informatics and data science at Yale School of Medicine, has developed a new algorithm capable of building complete human genomes using standard ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint ...

DNA methylation is a highly studied epigenetic modification that regulates genome function and plays key roles in development and disease 1. It is linked to a broad range of conditions, including ...

Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

The promise of genome editing to help understand human diseases and create new therapies is vast, but technological limitations have limited advancement of the field. While existing editing ...

A reanalysis of whole-genome data from 130 children conceived after the Chernobyl disaster has identified a statistically ...

The DNA damage from ionizing radiation (IR) erupting from the Chernobyl nuclear disaster of 1986 is showing up in the ...

Researchers reprogrammed bacterial bridge recombinases to edit large genomic regions in mammalian cells, revealing a ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...

Industrial yeasts are a powerhouse of protein production, used to manufacture vaccines, biopharmaceuticals, and other useful ...

A recent study confirms that children of Chernobyl cleanup workers exhibit significant DNA mutations linked to their fathers' ...

Ancient DNA from a 5,500-year-old skeleton in Colombia reveals the oldest genome of "Treponema pallidum" yet, sharpening ...