The majority of drug interactions today are attributed to the cytochrome P450 (CYP450) isoenzyme system. However, new data suggest that transport proteins also play a key role. One such transporter is ...

Severe acute respiratory syndrome virus 2 (SARS-CoV-2), the causative agent of coronavirus disease 19 (COVID-19), uses its spike (S) glycoprotein to enter host cells. The S glycoprotein consists of ...

Stanniocalcin-1 (STC1) is a glycoprotein hormone involved in calcium/phosphate homeostasis, which regulates various cellular processes in normal development and tumorigenesis. After analyzing more ...

3D structural findings are reported on a critical component of the Nipah virus' infection mechanism, and how antibodies home in on an important part of the machinery that attaches the virus to host ...

Using bioinformatic tools to examine similarities between human PDL-1 protein and common tobacco (Nicotiana tabacum). This is an ASCO Meeting Abstract from the 2020 ASCO-SITC Clinical Immuno-Oncology ...

Glycosylation is a critical quality attribute (CQA) for therapeutic proteins, influencing their stability, bioactivity, and immunogenicity. Glycoprotein characterization and glycosylation profiling ...

Please provide your email address to receive an email when new articles are posted on . A total of 88 metabolites were linked to increased risk for incident gout, glycoprotein acetyl being the most ...

When the Ebola virus infects a host cell, the first thing it does is attach itself to the cell using a glycoprotein. A newly obtained structure of that glycoprotein—the highest resolution one to ...

Replacing a step in sample preparation with an automated approach improves both method precision and productivity. Glycosylation is a critical quality attribute (CQA) for therapeutic proteins, ...