Many human cancers are caused by deregulation of specific transcription factors. To study the mechanisms by which transcriptional deregulation causes neoplasia, we are using a chromatin ...

Those cumbersome ChIP protocols are a thing of the past. Take two minutes and see how simple ChIP can really be. Seeing is believing, so get ready to believe in ...

Chromatin immunoprecipitation The Chromatrap® ChIP-seq Protein A kit (Cat no 500189) was used for ChIP in accordance with the protocol supplied in the kit. Slurries were prepared for ...

SUMOylation is an essential post-translational modification that regulates protein functions. All eukaryotes express at least one small ubiquitin-related modifier (SUMO) protein; higher eukaryotes ...

An invaluable source of RNA, DNA, and chromatin from historical and clinical samples is formalin fixed paraffin embedded (FFPE) tissue. Globally, tissue banks, hospitals, and laboratories are ...